Top 3 Most Addictive Anxiety Medications

anxiety medication pills

Updated on March 16th, 2021

Top 3 Most Addictive Anxiety Medications

Only intended for short-term use, benzodiazepines become less effective over time and the user’s risk of addiction increases.

Anxiety disorders affect nearly a quarter of the American population every year.1 People with anxiety disorders are also two to three times more likely than the general population to experience a substance use disorder at some point in their lives.2

Treatment methods for anxiety are well-researched topics and the first course of action is often cognitive behavioral therapy, which studies have shown to be extremely effective and long-lasting. However, in some cases, a person may suffer from excessive levels of anxiety, which can prevent them from getting the most out of their therapy.

Anti-anxiety medications (most commonly benzodiazepines) are generally safe and effective ways to treat the symptoms of anxiety, like insomnia or panic attacks. However, they are only intended for short-term use. Over time, benzodiazepines become less effective and the user’s risk of addiction increases.3

Due to the risks of physical dependence and addiction, most health experts do not recommend doctors prescribe benzodiazepines for longer than one month at a time.

How Do Anti-Anxiety Medicines Work?

There are several different types of medications that can be used to treat the symptoms of anxiety. According to the Anxiety and Depression Association of America, there are four main classes of drugs used to treat anxiety and each class of drug works differently.4

  1. Benzodiazepines – These drugs work by reducing muscle tension, promoting relaxation, and decreasing other physical symptoms of anxiety. They are generally used for short-term management of anxiety. Common generic names for benzodiazepines include alprazolam, clonazepam, diazepam, and lorazepam.
  2. Selective Serotonin Reuptake Inhibitors (SSRIs) – These drugs work by preventing certain nerve cells in the brain from reabsorbing serotonin. As a result, more serotonin is available, which improves mood and enhances the sending of nerve impulses. SSRI drugs only affect serotonin and not other neurotransmitters. Common generic names for SSRIs include citalopram, escitalopram, fluoxetine, paroxetine, and sertraline.
  3. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) – These drugs work by inhibiting the reabsorption of two neurotransmitters (serotonin and norepinephrine) to increase levels of both in the brain. Common generic names for SNRIs include venlafaxine and duloxetine.
  4. Tricyclic antidepressants – These drugs work by inhibiting the reabsorption of the neurotransmitters serotonin and norepinephrine. Of the four types of drugs used to treat anxiety, tricyclic antidepressants are less frequently used. Common generic names for tricyclic antidepressants include amitriptyline, imipramine, and nortriptyline.

Can You Get Hooked On Anxiety Medication?

Yes, anxiety medication can be highly addictive. Consistent use of anti-anxiety drugs can quickly cause physical dependence and withdrawal symptoms. Many people mistake withdrawal symptoms for a return of their anxiety, leading them to believe that they need to take more of the medication or begin using it again after their prescription has run out. Taking anti-anxiety drugs for long periods or taking more of the drugs than directed is likely to cause addiction.

Top 3 Most Addictive Anxiety Medications

There are many different types of anti-anxiety drugs, but these are some of the most addictive and commonly prescribed (listed in no particular order).

  1. Alprazolam (Xanax)
xanax pills

Xanax is one of the most commonly prescribed benzodiazepines in the United States and it is a Schedule IV drug. It is used to treat generalized anxiety disorder, various phobias, social anxiety disorder, and panic disorders. Xanax is a central nervous system depressant that produces feelings of calmness and relaxation. Its effects can be felt almost instantly, which contributes to the high rates of abuse in the U.S. According to the most recent National Survey on Drug Use and Health (NSDUH), 5.4 million people were past year misusers of prescription benzodiazepines like Xanax in 2018.5

  1. Clonazepam (Klonopin)
klonopin pills

Klonopin is another powerful prescription benzodiazepine that is used to treat panic attacks, anxiety, and seizure disorders. It is a Schedule IV drug that works by inducing feelings of relaxation and calmness. Although it is generally effective for medical treatment, it is highly addictive, even if it is taken for a short period. High doses of Klonopin can produce feelings of euphoria and can even cause hallucinations.6 Klonopin is very similar to Xanax, but its effects last up to two or three times longer. People who abuse Klonopin are at high risk for physical tolerance, addiction, or overdose. Quitting Klonopin without medical assistance can be difficult and dangerous.

  1. Diazepam (Valium)
valium pills

According to the DEA, Valium is one of the five most commonly prescribed benzodiazepines in the U.S. and one of the most frequently encountered benzos on the illicit market.7 It is a Schedule IV drug that works by relaxing muscles and preventing convulsions. Its effects typically last 20 to 70 hours and the drug starts to produce a sedative effect that can be felt within 30 to 60 minutes of taking a dose. Valium is both physically and psychologically addictive and when it is abused with other drugs or alcohol, it can be even more dangerous, potentially leading to an overdose.

Other Common Anxiety Medications That Can Be Addictive

  1. Lorazepam (Ativan)

Ativan is a benzodiazepine and it works by attaching to GABA receptors in the brain. Ativan is highly addictive so doctors usually only prescribe it for short-term use spanning 3 to 4 months. However, many people become physically dependent and abuse it. Heavy abuse of lorazepam or using lorazepam with alcohol or other drugs can cause insomnia, headaches, weakness, memory problems, anorexia, and anxiety. Quitting Ativan abruptly can also cause withdrawal symptoms such as depression, confusion, short-term memory loss, sweating, hallucinations, anxiety, delirium, and vertigo.

  1. Chlordiazepoxide (Librium)
librium pills

Librium is another habit-forming psychotropic drug that is used to treat anxiety. Misusing Librium in any way (especially for a prolonged time) can lead to dependence, withdrawal symptoms, and addiction. It’s a Schedule IV regulated drug and directly affects the brain and central nervous system to produce feelings of calmness and relaxation. People who misuse Librium often snort the contents of the capsules or mix the powder with water and inject it. Some people also use it to curb the side effects of powerful and illegal drugs like cocaine.

  1. Bromazepam (Lectopam)
bromazepam pills

Bromazepam is a generic drug that is sold under the brand name Lectopam (and several other brand names). It’s a benzodiazepine that is intended for short-term use. In low doses, it reduces anxiety and tension. In high doses, it acts as a sedative and muscle relaxer. People can become physically dependent on Lectopam even just taking it as prescribed. However, addiction is also likely to develop if someone takes larger doses, more frequent doses, or uses Lectopam for longer than prescribed. Lectopam has a high risk of abuse due to its fast-acting euphoric side effects.

  1. Oxazepam (Serax)
oxazepam pills

Serax is prescribed to treat anxiety and insomnia. It’s a benzodiazepine that increases the effects of GABA in the central nervous system. Serax is metabolized differently than other benzos and is less likely to accumulate in the user’s system. As such, it’s considered less addictive, however, it can still cause dependence and addiction if it is abused. People who take Serax with other substances to enhance its effects, take more than prescribed, take more frequent doses than necessary, or use it for longer than prescribed are more likely to develop an addiction.

  1. Clorazepate (Tranxene)
clorazepate pills

Tranxene is a benzodiazepine that is used to treat insomnia and anxiety disorders. It works by affecting the body’s GABA receptors to produce feelings of calmness, relaxation, and mild euphoria. These effects can cause dependence and addiction. People who become addicted to Tranxene often mix it with other substances to enhance its effects, use it for longer than necessary, or attempt to self-medicate for anxiety and stress-related issues. Once a person is addicted, abruptly quitting Tranxene can be dangerous. Withdrawal symptoms can include hallucinations, seizures, anxiety, insomnia, sweating, and tremors.

What Are Signs I Might Be Addicted to My Anxiety Medicine?

According to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, common signs that you might be addicted to your anxiety medication include:8

  • Taking your anxiety medicine for longer than intended.
  • Taking your anxiety medicine more often or in larger doses than prescribed.
  • Spending a considerable amount of time getting your anxiety medicine, using it, and recovering from its side effects.
  • Experiencing withdrawal symptoms after the effects of your anxiety medicine wear off.
  • Needing larger doses of your anxiety medicine to achieve the same results.
  • Experiencing impaired performance at school, home, or work due to the effects of your anxiety medication.
  • Trying to quit or control your use of anxiety medication but failing.
  • Experiencing strong cravings for your anxiety medicine.

If you think you might be addicted to your anxiety medication, you should speak with your doctor immediately.

Is There a Non-Addictive Anxiety Medication?

There are a few different types of drugs that are marketed as being non-addictive anti-anxiety medications, but all drugs have potential side effects and risks to consider.

  • SSRIs are generally effective at reducing symptoms of anxiety, but it can take four to six weeks of using an SSRI before you start feeling the full effects. Although they are not considered physically addictive, you can still develop a psychological addiction to SSRIs like Prozac, Lexapro, Celexa, Paxil, and Zoloft, which can cause problems in your daily life. SSRIs can also cause uncomfortable withdrawal symptoms if you suddenly stop taking them.9
  • SNRIs are also not considered addictive, but they can still cause psychological dependence and may produce uncomfortable withdrawal symptoms if you suddenly stop using them.10
  • Buspar (buspirone) is another anxiety medication that is similar to an SSRI. The main difference between Buspar and SSRI drugs is that it only affects one specific area of the brain. As a result, it produces fewer side effects. Buspar is not known to be addictive and it is frequently used to treat people with anxiety and substance use disorders. It does not cause tolerance or withdrawal symptoms and it is not a controlled substance in the U.S. However, you will need a valid prescription to get Buspar.
  • Vistaril (hydroxyzine) is often used to treat generalized anxiety disorder. It works by blocking the effects of histamine in your body, which will make you feel very sleepy.10 Although it is a versatile and effective drug for anxiety, hydroxyzine is intended for short-term treatment of anxiety and is not a long-term solution.

What Are Some Natural Remedies for Anxiety?

There are also many different ways to reduce symptoms of anxiety naturally without medication. Although some anxiety may be substance abuse related and require professional addiction treatment and/or medication, here are some alternative options you can discuss with your doctor:

  • Stop drinking alcohol and/or smoking
  • Exercise regularly
  • Reduce your caffeine intake
  • Practice meditation
  • Practice healthy sleep hygiene
  • Eat a healthy and varied diet (limit sugar and processed foods)
  • Use deep breathing exercises
  • Try supplements like Passionflower, Valerian root, and Rhodiola
  • Take your vitamins (omega-3 fatty acids, B vitamins, probiotics, and L-theanine can all help reduce symptoms of anxiety)

If you are struggling to deal with severe symptoms of anxiety, you should talk to your doctor about the best treatment options. Suffering from addiction and anxiety simultaneously is not uncommon. Fortunately, a multidisciplinary approach that combines medical and clinical care for both disorders can help resolve the issues that are preventing you from living your best life.

Treatment for Anxiety Medication Addiction

Various anxiety medications may be helpful to manage anxiety disorders but many of them are also highly addictive. If you or a loved one is addicted to your anxiety medication, the safest way to stop abusing it is by getting professional help. At Briarwood Detox Center, our medical detox program for anxiety medication addiction will provide round-the-clock medical treatment for withdrawal symptoms. We also provide clinical treatment from licensed counselors to help you manage the psychological symptoms of drug withdrawal.

If and when you are able, you may also attend group therapy meetings. These sessions will provide additional guidance and support as you process your emotions and feelings related to getting sober.

Treatment during medical detox not only ensures your physical health and safety but also helps you stay sober through the most difficult aspects of withdrawal. We provide compassionate assistance and support to ensure that you have access to appropriate treatment and care after detox is over. Getting the proper care will help you stay sober and achieve long-lasting sobriety.

If you’d like to learn more about drug and alcohol detox programs and treatment for co-occurring disorders like anxiety, call (888) 857-0557 to speak with a Briarwood Detox Center representative today. We accept most forms of insurance for detox.


  1. https://adaa.org/about-adaa/press-room/facts-statistics
  2. https://adaa.org/understanding-anxiety/related-illnesses/substance-abuse
  3. https://www.aafp.org/afp/2013/0815/p224.html
  4. https://adaa.org/learn-from-us/from-the-experts/blog-posts/what-medications-are-used-treat-anxiety-disorders
  5. https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/NSDUHNationalFindingsReport2018/NSDUHNationalFindingsReport2018.pdf
  6. https://www.drugs.com/klonopin.html
  7. https://www.deadiversion.usdoj.gov/drug_chem_info/benzo.pdf#search=benzodiazepines
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767415/
  9. https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825
  10. https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970
  11. https://www.goodrx.com/blog/hydroxyzine-for-anxiety-how-it-works-side-effects-cost/

Our center is in-network with many insurances

bcbs logo
united healthcare logo
cigna logo
aetna logo
magellan logo
beacon logo
Call (888) 857-0557 to verify your benefits.

Break Free From Your Addiction Today

(in 3 easy, confidential steps)

insurance form

Verify your insurance

Complete our fast, free, and easy verification process over the phone to determine the extent of your insurance coverage.


Make an informed decision

We will provide personalized placement recommendations based on your insurance, treatment needs, financial situation, and schedule.

contact us

Contact us

Call (888) 857-0557 or fill out our online form for a free and confidential personal consultation with an admissions specialist.

Get Help Now

    Call Now Button