Can You Have Seizures from Lyrica Withdrawal in Austin, TX?

Published on November 27, 2025
Detox: Austin, Drug Addiction, Drug and Alcohol Detox, Mental Health

Key Takeaways

Lyrica changes how nerve cells communicate, and long‑term use can lead to physical dependence on the medication.
Lyrica withdrawal happens when the body has adapted to pregabalin and the dose is reduced or stopped too quickly.
Yes, seizures can occur during Lyrica withdrawal, particularly in people with seizure disorders, high doses, or abrupt discontinuation.
Lyrica withdrawal can also cause a range of physical and psychological symptoms, including flu‑like illness, anxiety, and insomnia.
Withdrawal symptoms usually begin within a day of the last dose, peak in the first week, and in some cases may linger for weeks.
Trying to manage Lyrica withdrawal alone can be risky, and medically supervised detox offers safer monitoring and symptom management.
Briarwood Detox Center in Austin, TX provides structured Lyrica detox with 24/7 care and planning for ongoing substance abuse treatment Austin TX.

Break Free from Addiction. Detox Safely in Austin Today.

Medically Supervised Detox – Compassionate Care Starts Here.

Lyrica (pregabalin) is commonly prescribed for nerve pain, fibromyalgia, and certain seizure disorders. It acts on the central nervous system and changes how nerve cells send signals. When the medication is reduced too quickly or stopped suddenly, the nervous system can react in unpredictable ways.

One possible and serious reaction is a seizure. This can happen even in people who did not have seizures before taking Lyrica, though the risk is higher in those with a seizure history or those taking high doses.

This article explains how and why seizures can occur during Lyrica withdrawal, what other symptoms to expect, and how medically supervised detox at Briarwood Detox Center in Austin, TX can help you stop Lyrica as safely as possible.

What Is Lyrica and How Does It Work?

Common medical uses

Lyrica is an anticonvulsant, or anti‑seizure, medicine. It is FDA‑approved to treat:

Partial‑onset seizures in adults
Neuropathic pain related to diabetes, shingles, or spinal cord injury
Fibromyalgia

The drug binds to calcium channels in the brain and spinal cord, which reduces the release of several excitatory neurotransmitters. This dampens overactive nerve signaling and can ease pain and prevent certain seizures.

Why dependence and tolerance can develop

With ongoing use, the brain adjusts to the constant presence of pregabalin. Over time, some people need higher doses to get the same effect (tolerance). Others notice that if they miss doses or cut down too quickly, they feel unwell, anxious, or physically uncomfortable.

This is physical dependence. It does not automatically mean a person has an addiction, but it does mean that stopping Lyrica suddenly can cause withdrawal symptoms and, in some cases, seizures.

What Happens During Lyrica Withdrawal?

Physical dependence vs. addiction

Physical dependence means the body has adapted to Lyrica and reacts when the drug level falls.
Addiction involves loss of control over use, cravings, and continued use despite harm.

Someone can be physically dependent on Lyrica even when using it exactly as prescribed. Addiction is more likely when pregabalin is taken at high doses, for non‑medical reasons, or combined with other substances such as opioids, alcohol, or benzodiazepines.

How withdrawal develops

When Lyrica is reduced or stopped, the nervous system suddenly loses the calming effect it has been relying on. This can lead to:

Overactive nerve firing
Rebound anxiety or pain
Changes in sleep, mood, and gut function

In most people, these changes cause uncomfortable but non‑life‑threatening symptoms. In a smaller group, the sudden shift can trigger seizures or severe psychiatric symptoms such as agitation or psychosis.

Can You Have Seizures from Lyrica Withdrawal?

Yes. Seizures are a documented complication of Lyrica withdrawal.

People with seizure disorders

The FDA prescribing information for Lyrica and Lyrica CR emphasizes that the medication should be tapered gradually over at least one week. Stopping suddenly may increase seizure frequency in people who take Lyrica for epilepsy or other seizure disorders.

If Lyrica has been part of a seizure‑control plan and is removed too quickly, the brain can become more excitable. This may lead to:

A return of previous seizures
More frequent or more severe seizures than before
Rarely, prolonged seizures that require emergency treatment

People taking Lyrica for pain, fibromyalgia, or anxiety

Case reports show that seizures can also occur when people without a seizure history stop pregabalin abruptly, especially after long‑term or high‑dose use.

While this appears less common, the risk is still taken seriously. Recent clinical reviews and safety updates on gabapentinoids (the drug class that includes Lyrica) warn that rapid discontinuation may trigger seizures and other serious withdrawal reactions.

Why tapering is safer than stopping “cold turkey”

A taper allows the brain to adjust slowly as the dose is reduced. Most guidelines recommend lowering the dose over at least a week, and often longer in people who:

Take high daily doses
Have used Lyrica for several months or longer
Also use alcohol, opioids, benzodiazepines, or other sedatives
Have a history of seizures or serious mental health conditions

Because of these variables, supervised detox in a medical setting is often the safest path for Lyrica withdrawal.

Other Lyrica Withdrawal Symptoms to Expect

Physical symptoms

Common physical symptoms reported during pregabalin withdrawal include:

Headaches
Nausea, vomiting, or diarrhea
Sweating and chills
Muscle aches or increased pain sensitivity
Fatigue and flu‑like feelings
Tremors or shakiness
Rapid heartbeat or palpitations

Seizures are less common but are considered a medical emergency.

Psychological and sleep‑related symptoms

Because Lyrica affects mood and sleep, withdrawal can also cause:

Anxiety, restlessness, or panic
Irritability, anger, or mood swings
Depressed mood or hopelessness
Trouble falling or staying asleep
Vivid dreams or nightmares
In rare cases, confusion, hallucinations, or psychosis

These symptoms are distressing and can increase relapse risk if not well managed.

Break Free from Addiction. Detox Safely in Austin Today.

Medically Supervised Detox – Compassionate Care Starts Here.

Lyrica Withdrawal Timeline

Everyone’s experience is different, but published case reports and clinical resources suggest a general pattern.

First 24–48 hours

Initial symptoms may begin within 12–24 hours after the last dose.
Anxiety, irritability, and sleep problems are common early signs.
People taking Lyrica for seizures may notice aura symptoms or increased seizure activity.

Days 2–7: Acute withdrawal

Physical symptoms such as headaches, sweating, stomach upset, and flu‑like discomfort often peak.
Seizures, if they occur, usually appear during this acute period.
Mood changes, agitation, and cravings can be intense.

Most acute symptoms start to improve after several days, especially when withdrawal is medically supported.

After the first week: Lingering symptoms

Some people continue to have insomnia, anxiety, or low mood for several weeks.
Pain conditions may temporarily feel worse as the nervous system recalibrates.
For a few individuals, post‑acute symptoms can persist longer, especially after long‑term high‑dose use or when other mental health conditions are present.

Factors That Increase Withdrawal and Seizure Risk

Dose, duration, and taper speed

Higher doses, long‑term use, and fast tapers all increase the chance of significant withdrawal symptoms, including seizures.

Co‑occurring medical and mental health conditions

People with the following may face extra risk:

Epilepsy or a prior seizure history
Kidney disease (which can raise pregabalin levels)
Breathing problems or sleep apnea
Depression, bipolar disorder, or psychosis

Serious mental health symptoms, including suicidal thoughts, have been reported during pregabalin use and withdrawal, so close monitoring is important.

Other medications and substances

Combining Lyrica with alcohol, opioids, benzodiazepines, or other sedatives can:

Increase respiratory depression risk
Make withdrawal more complicated
Raise the chance of overdose or severe withdrawal reactions

Because of these interactions, supervised detox is strongly recommended when Lyrica is part of a broader pattern of substance use.

Why Medical Detox Is Recommended for Lyrica Withdrawal

Limits of stopping at home

Some people try to taper Lyrica on their own. Without medical monitoring, they may:

Reduce the dose too quickly
Miss subtle warning signs of seizures or severe mood symptoms
Use alcohol or other drugs to cope with discomfort

This can lead to ER visits, relapse, or unsafe dosing changes.

Advantages of 24/7 medical monitoring

In a medical detox setting, clinicians can:

Design a gradual, individualized taper
Monitor vital signs and neurologic status
Use non‑addictive medications to ease symptoms like nausea, insomnia, or anxiety
Respond immediately if seizure activity or severe agitation occurs

For someone who has already experienced withdrawal symptoms from Lyrica—or who is at higher risk because of medical history—this level of structure can reduce danger and distress.

Lyrica Withdrawal Care at Briarwood Detox Center in Austin, TX

Briarwood Detox Center provides medically supervised detox for Lyrica and other prescription medications through its dedicated prescription drug detox program. Care is delivered in a structured environment with 24/7 clinical oversight.

Comprehensive assessment and personalized plan

On admission, the team reviews:

Lyrica dose, schedule, and length of use
Other medications or substances
Medical history, including seizure disorders or kidney problems
Mental health symptoms and stressors

This information guides a tailored taper schedule and symptom‑management plan.

Managing seizures and other complications

If someone is at risk for withdrawal seizures, staff can:

Monitor for early neurologic changes
Coordinate with prescribing or consulting physicians
Adjust the taper rate when needed
Provide rapid intervention if seizure activity occurs

The goal is to minimize discomfort, support safety, and stabilize the nervous system during withdrawal.

Preparing for ongoing substance abuse treatment in Austin, TX

Many people who search for “substance abuse treatment Austin TX,” “drug treatment centers in Austin,” “Austin drug treatment centers,” or “drug treatment centers Austin Texas” are in the early stages of seeking help. Detox at Briarwood often serves as the first step before entering longer‑term residential or outpatient care.

During Lyrica detox, Briarwood staff help plan the next phase of treatment so that progress made during withdrawal is not lost.

You can learn more about the Austin facility and its medically supervised environment on the
Austin drug detox center page.

How Briarwood Fits Into Your Recovery Journey

A focused start to prescription drug recovery

For people struggling with Lyrica dependence alone or as part of a broader prescription drug pattern, detox provides a structured reset. Briarwood’s
existing Lyrica withdrawal resources and on‑site clinical team help you understand what is happening in your body while you taper safely.

Support beyond the detox phase

As withdrawal symptoms ebb, staff work with you to:

Clarify recovery goals
Identify appropriate follow‑up care (such as residential rehab, intensive outpatient programs, or other services)
Coordinate referrals and verify insurance coverage

This continuity reduces gaps between detox and ongoing treatment, which is important for long‑term stability.

When to Seek Immediate Help

Seek emergency medical care right away if you or someone else:

Has a seizure
Cannot stay awake or breathe normally
Experiences chest pain, severe confusion, or sudden behavior changes
Talks about wanting to die or self‑harm

After urgent medical needs are addressed, a planned, medically supervised detox can lower the chance of another crisis.

If you are considering stopping Lyrica, are already feeling withdrawal symptoms, or are concerned about seizure risk, Briarwood Detox Center can explain your options and help you plan a safer path forward.

Call our admissions team today at (888) 857-0557.

How Briarwood Detox Center in Austin Helps With Lyrica Withdrawal

Briarwood Detox Center in Austin provides medically supervised care for people who want to stop Lyrica safely. A licensed team reviews your Lyrica dose, medical history, and other medications before detox begins. They design an individualized taper to lessen withdrawal symptoms and reduce seizure risk. During your stay, staff monitor you around the clock, track vital signs, and respond quickly if complications arise. Non‑addictive medications and supportive care can ease anxiety, pain, and sleep problems linked to Lyrica withdrawal. The structured setting also helps limit access to substances that might interfere with your progress. For individuals searching for substance abuse treatment Austin TX or Austin drug treatment centers, this local program offers a focused and secure first step. Briarwood Detox Center guides you through Lyrica withdrawal as safely as possible and prepares you for the next phase of treatment that matches your long‑term recovery goals.

Start Lyrica Withdrawal Detox at Our Texas Locations

Safe Prescription Drug Detox in Austin

Outpatient Detox for Lyrica Withdrawal in San Antonio

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Medical Disclaimer

The information on this page is intended for general education about Lyrica withdrawal and related health topics. It is not a substitute for professional medical advice, diagnosis, or treatment from a licensed clinician. Prescription medications, including antidepressants, antipsychotics, and drugs like Lyrica, should only be started, adjusted, or stopped under the guidance of a qualified healthcare provider. Never change your dose or discontinue a medication without first speaking with your doctor or prescriber. If you experience severe side effects, rapidly worsening symptoms, or thoughts of self‑harm, call 911 in the United States or seek emergency medical care right away. You can also dial 988 at any time to reach the Suicide & Crisis Lifeline for confidential emotional support. Briarwood Detox Center offers medically supervised detox services but does not replace emergency services or your personal medical team.

Lyrica Withdrawal and Detox FAQs

What are the symptoms of Lyrica withdrawal?

Lyrica (pregabalin) withdrawal can cause both physical and emotional symptoms. Many people report anxiety, irritability, trouble sleeping, headaches, sweating, nausea, and flu‑like discomfort. Some notice increased pain, tremors, or a racing heartbeat. Mood changes such as low mood or agitation can also appear. In higher‑risk cases, withdrawal may trigger seizures or severe confusion, which need urgent medical attention.

How long does Lyrica withdrawal usually last?

Lyrica withdrawal often begins within one to two days after the last dose. For many people, the most intense symptoms last several days to about one week. Some individuals, especially those who used high doses or took Lyrica for a long time, may notice lingering anxiety, insomnia, or changes in pain for several weeks. A gradual, medically supervised taper can shorten and soften this process compared with stopping suddenly.

Can Lyrica withdrawal cause seizures?

Yes. Seizures are a known but less common complication of Lyrica withdrawal. The risk is higher in people who take pregabalin for a seizure disorder, use large doses, or stop the medication abruptly. Seizures can also occur in people without a previous seizure history, which is why medical supervision is strongly recommended when discontinuing Lyrica.

Can you stop taking Lyrica (pregabalin) cold turkey?

Stopping Lyrica “cold turkey” is not recommended for most people. Abrupt discontinuation increases the chance of withdrawal symptoms such as anxiety, insomnia, and nausea, and it can raise the risk of Lyrica withdrawal seizures. Most prescribing guidelines advise reducing the dose gradually over at least a week, and often longer, based on your medical history and current dose.

Is Lyrica addictive or habit forming?

Lyrica is not an opioid, but it can lead to physical dependence and, in some cases, misuse or addiction. People may develop tolerance, cravings, or difficulty cutting back, especially when using higher doses or combining Lyrica with other substances. When dependence is present, pregabalin withdrawal can be uncomfortable and sometimes dangerous without support.

How do you safely come off Lyrica?

The safest way to stop Lyrica is with a slow, planned taper that is supervised by medical professionals. At Briarwood Detox Center, clinicians review your dose, duration of use, and seizure risk, then create a personalized taper schedule and monitor you around the clock for pregabalin withdrawal symptoms. Non‑addictive medications and supportive care can help ease discomfort, lower seizure risk, and keep you as stable as possible while your body adjusts. If you are ready to talk about a safe plan to stop Lyrica, Call our admissions team today at (888) 857-0557.

Do I need medical detox for Lyrica withdrawal?

Not everyone will need inpatient detox, but medical detox is often recommended for people who have used high doses, taken Lyrica for a long time, or have a history of seizures or other substance use. Briarwood Detox Center provides a structured, medically supervised setting in Austin, TX where you can complete Lyrica withdrawal with 24/7 monitoring and support before moving into ongoing substance abuse treatment Austin TX options that fit your needs. To learn whether medical detox is appropriate in your situation, Call our admissions team today at (888) 857-0557.Call our admissions team today at (888) 857-0557.